Does methotrexate affect the liver

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Methotrexate can lead to serious liver disease, portal hypertension, fibrosis and cirrhosis, usually with long term use particularly when given in daily regimens and in higher doses. Various guidelines have been .. Holst R, Mobacken H. [Liver damage during methotrexate treatment of psoriasis]. Nord Med ; Other medicationsā€ˇ: ā€ˇSalicylate g/day, predni. methotrexate can harm your liver. you'll visit the doctor regularly to check on how it affects your body.

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Methotrexate may cause liver damage, especially when it is taken for a long period of time. If you drink or have ever drunk If you do develop lymphoma, it might go away without treatment when you stop taking methotrexate, or it might need to be treated with chemotherapy. If you are taking methotrexate to. Unfortunately, depleting the body of folate can affect healthy cells, too, especially those in the gastrointestinal (GI) tract, mouth, hair follicles and liver, says Prabha Ranganathan, MD, an associate professor of medicine in the division of rheumatology at Washington University School of Medicine. GI problems such as nausea.

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